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Showing 1 to 12 of 177 entries
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Killing Mechanisms of Cytotoxic T Lymphocytes.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Groscurth P, Filgueira L.
PMID: 11390753
News Physiol Sci. 1998 Feb;13:17-21. doi: 10.1152/physiologyonline.1998.13.1.17.

Cytotoxic T lymphocytes mediate lysis of target cells by various mechanisms, including exocytosis of lytic proteins (perforin, granzymes) and receptor-ligand binding of Fas/APO molecules. Death of target cells is characterized by either necrosis or apoptosis, depending on the killing...

The Tuned Cricket.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Michelsen A.
PMID: 11390756
News Physiol Sci. 1998 Feb;13:32-38. doi: 10.1152/physiologyonline.1998.13.1.32.

Communication by means of sound is not always easy. Sound suffers much attenuation and degradation close to ground. Crickets have adapted to this by exploiting sharply tuned mechanical systems. A coevolution ensures that the calling song of males and...

Understanding the Role of Paracellular Transport in the Proximal Tubule.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

García NH, Ramsey CR, Knox FG.
PMID: 11390757
News Physiol Sci. 1998 Feb;13:38-43. doi: 10.1152/physiologyonline.1998.13.1.38.

Fluid and solute reabsorption by the proximal tubule is the result of both transcellular and paracellular flux. The role of transcellular transport has been extensively studied, but the importance of paracellular flux has not been as thoroughly investigated. The...

Cyclic Nucleotide Phosphodiesterases: New Role in the Pathogenesis of Glomerulonephritis?.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Dousa TP.
PMID: 11390760
News Physiol Sci. 1998 Feb;13:51-52. doi: 10.1152/physiologyonline.1998.13.1.51.

No abstract available.

Calcium Mobilization Systems During Neurogenesis.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Yamashita M, Sugioka M.
PMID: 11390766
News Physiol Sci. 1998 Apr;13:75-79. doi: 10.1152/physiologyonline.1998.13.2.75.

Neuroepithelial cells have Ca(2+) mobilization systems that are activated by acetylcholine via muscarinic receptors and by extracellular ATP via P(2U) purinoceptors. The Ca(2+) mobilization occurs during neurogenesis and diminishes in parallel with the declining of mitotic activities of the...

Visceral Afferent Neurons: Role in Gastric Mucosal Protection.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Holzer P, Pabst MA.
PMID: 11390851
News Physiol Sci. 1999 Oct;14:201-206. doi: 10.1152/physiologyonline.1999.14.5.201.

Gastric mucosal homeostasis requires rapid alarm of protective mechanisms in the face of pending injury. This article summarizes the evidence that spinal afferent neurons monitor insults to the gastric mucosa and activate local mechanisms of defense and repair through...

Prolactin, the Hormone of Paternity.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Schradin C, Anzenberger G.
PMID: 11390856
News Physiol Sci. 1999 Dec;14:223-231. doi: 10.1152/physiologyonline.1999.14.6.223.

Prolactin has long been known to play a significant role in maternal care. When behavioral endocrinologists began to examine the endocrinology of fatherhood, prolactin was also found to be connected with paternal care in fish, birds, and mammals including...

Sensorimotor Integration at the Dorsal Column Nuclei.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Mariño J, Martinez L, Canedo A.
PMID: 11390857
News Physiol Sci. 1999 Dec;14:231-237. doi: 10.1152/physiologyonline.1999.14.6.231.

Interaction among primary afferents, corticofugal fibers, and intrinsic elements allows for sensorimotor integration at the dorsal column nuclei. The interneurons permit the spatial localization, the recurrent collaterals synchronize the activity of projecting cells with overlapping receptive fields, and the...

Atrial Natriuretic Peptide: Regulator of Chronic Arterial Blood Pressure.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Melo LG, Pang SC, Ackermann U.
PMID: 11390897
News Physiol Sci. 2000 Jun;15:143-149. doi: 10.1152/physiologyonline.2000.15.3.143.

Recent findings in atrial natriuretic peptide (ANP) transgenic and gene knockout mouse models uncovered a tonic vasodilatory effect of this hormone that contributes to chronic blood pressure homeostasis. With elevated salt intake, ANP-mediated antagonism of the renin-angiotensin system is...

Stimulatory and Inhibitory Functions of the R Domain on CFTR Chloride Channel.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Ma J.
PMID: 11390899
News Physiol Sci. 2000 Jun;15:154-158. doi: 10.1152/physiologyonline.2000.15.3.154.

CFTR is a chloride channel whose gating process involves coordinated interactions among the regulatory (R) domain and the nucleotide-binding folds (NBFs). Protein kinase A phosphorylation of serine residues renders the R domain from inhibitory to stimulatory and enables ATP...

Endothelial Gaps: Plasma Leakage During Inflammation.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

McDonald DM.
PMID: 11390771
News Physiol Sci. 1998 Apr;13:104-105. doi: 10.1152/physiologyonline.1998.13.2.104.

No abstract available.

Maxi-K(Ca), a Unique Member of the Voltage-Gated K Channel Superfamily.

News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

Toro L, Wallner M, Meera P, Tanaka Y.
PMID: 11390773
News Physiol Sci. 1998 Jun;13:112-117. doi: 10.1152/physiologyonline.1998.13.3.112.

Large-conductance, voltage-, and Ca(2+)-sensitive K(+) (maxi-K(Ca)) channels regulate neuronal and smooth muscle excitability. Their pore-forming alpha-subunit shows similarities with voltage-gated channels and indeed can open in the practical absence of Ca(2+). The NH(2) terminus is unique, with a seventh...

Showing 1 to 12 of 177 entries